Dietrich Bonhoeffer, Creation and Fall: A Theological Exposition of Genesis 1–3 (Augsburg, 1997), 28:

Humankind no longer lives in the beginning; instead it has lost the beginning. Now it finds itself in the middle, knowing neither the end nor the beginning, and yet knowing that it is in the middle. It knows therefore that it comes from the beginning and must move on towards the end. It sees its life as determined by these two factors, concerning which it knows only that it does not know them. The animals know nothing about the beginning and the end; they therefore know no hatred and no pride. Humankind knows itself to be totally deprived of its own self-determination, because it comes from the beginning and is moving toward the end without knowing what that means. This makes it hate the beginning and rise up in pride against it.

HT:T-Bomb